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Fig. 5 | Chinese Medicine

Fig. 5

From: Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa

Fig. 5

Characterizing the mechanism of antibiofilm activity of quinic acid. a Volcano plot displaying DEGs between the control group and the group treated with LJF at 1/4 MIC. b GO analyses for DEGs. BP Biological process, CC Cellular components, MF Molecular function. c KEGG pathway enrichment analysis of DEGs. d Hierarchical clustering of DEGs. e qRT-PCR validation for detecting the level of selected DEGs. f Computational docking of quinic acid binding to RhlR, RhlA and RhlB in PA. Blue line indicates hydrogen bonding. *P < 0.05, **P < 0.01, compared with corresponding control

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