Fig. 4From: The emerging possibility of the use of geniposide in the treatment of cerebral diseases: a reviewThe therapeutic effect of geniposide on depression and other brain diseases. Geniposide downregulates the expression level of proinflammatory cytokines and upregulates the expression of GLP-1R/protein kinase B (AKT) signal-related proteins. It can also further upregulate the mRNA expression of BDNF and TrkB in diabetic mice to treat depressive behaviourBack to article page