Fig. 3

Core constituents and hub targets of SHD in UC. A Compound-Target network of SHD. Pink nodes represent CR, green nodes represent SR, yellow nodes represent RR, and blue nodes represent the targets. The purple node A represents a compound shared by SR and RR; the purple nodes B1 and B2 represent compounds shared by CR and SR. B Venn diagram of targets shared by SHD and UC. C The topological screening for the PPI network. D Network of core constituents and targets. E The numbers of targets for the 9 core substituents