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Table 1 The potential active compounds and targets in SHD

From: Systems pharmacology and transcriptomics reveal the mechanisms of Sanhuang decoction enema in the treatment of ulcerative colitis with additional Candida albicans infection

Drug Molecule name OB (%) DL Target number
CR1 berberine 36.86 0.78 17
CR Obacunone 43.29 0.77 0
CR2 berberrubine 35.74 0.73 13
CR(B1) epiberberine 43.09 0.78 11
CR3 (R)-Canadine 55.37 0.77 31
CR4 Berlambine 36.68 0.82 20
CR5 Corchoroside A_qt 104.95 0.78 2
CR6 Magnograndiolide 63.71 0.19 4
CR Palmidin A 35.36 0.65 0
CR7 palmatine 64.6 0.65 19
CR8 quercetin 46.43 0.28 154
CR(B2) coptisine 30.67 0.86 9
CR9 Worenine 45.83 0.87 7
CR Moupinamide 86.71 0.26 0
SR1 acacetin 34.97 0.24 26
SR2 wogonin 30.68 0.23 45
SR3 (2R)-7-hydroxy-5-methoxy-2-phenylchroman-4-one 55.23 0.2 21
SR4 baicalein 33.52 0.21 37
SR 5,8,2ʹ-Trihydroxy-7-methoxyflavone 37.01 0.27 0
SR5 5,7,2,5-tetrahydroxy-8,6-dimethoxyflavone 33.82 0.45 13
SR6 Carthamidin 41.15 0.24 4
SR 2,6,2ʹ,4ʹ-tetrahydroxy-6ʹ-methoxychaleone 69.04 0.22 0
SR7 Dihydrobaicalin_qt 40.04 0.21 3
SR8 Eriodyctiol (flavanone) 41.35 0.24 8
SR9 Salvigenin 49.07 0.33 18
SR10 5,2ʹ,6ʹ-Trihydroxy-7,8-dimethoxyflavone 45.05 0.33 17
SR11 5,7,2ʹ,6ʹ-Tetrahydroxyflavone 37.01 0.24 6
SR dihydrooroxylin A 38.72 0.23 0
SR12 Skullcapflavone II 69.51 0.44 21
SR13 oroxylin a 41.37 0.23 26
SR14 Panicolin 76.26 0.29 14
SR15 5,7,4ʹ-Trihydroxy-8-methoxyflavone 36.56 0.27 18
SR16 NEOBAICALEIN 104.34 0.44 22
SR17 DIHYDROOROXYLIN 66.06 0.23 11
SR(A) beta-sitosterol 36.91 0.75 38
SR18 sitosterol 36.91 0.75 3
SR19 Norwogonin 39.4 0.21 12
SR20 5,2ʹ-Dihydroxy-6,7,8-trimethoxyflavone 31.71 0.35 21
SR21 ent-Epicatechin 48.96 0.24 6
SR22 Stigmasterol 43.83 0.76 31
SR(B2) coptisine 30.67 0.86 9
SR23 bis[(2S)-2-ethylhexyl] benzene-1,2-dicarboxylate 43.59 0.35 1
SR Supraene 33.55 0.42 0
SR24 Diop 43.59 0.39 3
SR(B1) Epiberberine 43.09 0.78 11
SR25 Moslosooflavone 44.09 0.25 25
SR26 11,13-Eicosadienoic acid, methyl ester 39.28 0.23 1
SR27 5,7,4ʹ-trihydroxy-6-methoxyflavanone 36.63 0.27 6
SR28 5,7,4ʹ-trihydroxy-8-methoxyflavanone 74.24 0.26 6
SR29 rivularin 37.94 0.37 22
RR1 EUPATIN 50.8 0.41 16
RR Mutatochrome 48.64 0.61 0
RR2 Physciondiglucoside 41.65 0.63 1
RR Procyanidin B-5,3ʹ-O-gallate 31.99 0.32 0
RR3 rhein 47.07 0.28 7
RR Sennoside E_qt 50.69 0.61 0
RR4 Torachrysone-8-O-beta-d-(6ʹ-oxayl)-glucoside 43.02 0.74 1
RR5 Toralactone 46.46 0.24 9
RR6 Emodin-1-O-beta-d-glucopyranoside 44.81 0.8 1
RR Sennoside D_qt 61.06 0.61 0
RR7 Daucosterol_qt 35.89 0.7 2
RR palmidin A 32.45 0.65 0
RR (A) beta-sitosterol 36.91 0.75 38
RR8 aloe-emodin 83.38 0.24 24
RR gallic acid-3-O-(6ʹ-O-galloyl)-glucoside 30.25 0.67 0
RR9 (−)-catechin 49.68 0.24 11