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Table 1 Active compounds and their corresponding parameters in HGWD formula

From: Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress

No

CAS

Compounds

Herb

Degree

Structure

1

480-18-2

Taxifolin

CR/ AR

13

2

486-39-5

(S)-Coclaurine

JF

13

3

470-82-6

1,8-cineole

ZR

10

4

99-50-3

3,4-dihydroxybenzoicacid

CR

20

5

N/A

3,9-di-O-methylnissoln

AR

11

6

77398-90-4

4-gingerol

ZR

1

7

23513-14-6

6-gingerol

ZR

21

8

555-66-8

6-shogaol

ZR

17

9

2086-83-1

Berberine

JF

19

10

20575-57-9

Calycosin

AR

20

11

104-55-2

Cinnamaldehyde

CR

25

12

N/A

Cinnamic acid

CR

23

13

N/A

Coumestrol

JF

15

14

485-72-3

Formononetin

AR

38

15

130-86-9

Fumarine

JF

14

16

465-99-6

Hederagenin

AR

10

17

480-19-3

Isorhamnetin

AR

31

18

3301-49-3

Jaranol

AR

15

19

520-18-3

Kaempferol

AR/ PRA

45

20

32383-76-9

Medicarpin

AR

3

21

117-39-5

Quercetin

AR/ JF

69

22

92-61-5

Scopoletin

JF

15

23

2810-21-1

Stepharine

JF

11

24

16562-13-3

Stepholidine

JF

3

25

83-48-7

Stigmasterol

AR/ZR/ JF

17

26

122-48-5

Zingerone

ZR

11

27

83-46-5

Beta-sitosterol

CR/ ZR/ PRA/ AR/ JF

22

28

23180-57-6

Paeoniflorin

AR/PRA

14

29

472-15-1

Betulic acid

PRA/ AR/ JF

2

30

73536-69-3

Bifendate

AR

6