Fig. 1

Comparison of history, products, active constituents, clinical trials and patens of two Rhodiola species. A Basic information of R. crenulata and R. rosea. B Representative products developed based on R. crenulata and R. rosea. C Number of main active constituents contained in R. crenulata and R. rosea. D Advanced in clinical trials of R. crenulata and R. rosea. Data collected from PubMed (searching term of “Rhodiola” plus flter of “Clinical trial”, language limited to English) and ClinicalTrials.gov (searching term of “Rhodiola”) as of 15 June 2021. E Patent application of R. crenulata and R. rosea. Data collected from the Lens (https://www.lens.org, Searching term: Rhodiola) as of 15 June 2021