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Fig. 3 | Chinese Medicine

Fig. 3

From: Alpinia oxyphylla Miq extract reduces cerebral infarction by downregulating JNK-mediated TLR4/T3JAM- and ASK1-related inflammatory signaling in the acute phase of transient focal cerebral ischemia in rats

Fig. 3

Effects of YZR-0.4 g and YZR-0.8 g treatments on cytosolic p-ASK1, ASK, MyD88, TRAF6, T3JAM, TRAF3, and Iba1 expression in the penumbral cortex. A Representative Western blot images showed cytosolic p-ASK1, ASK, MyD88, TRAF6, T3JAM, TRAF3, and Iba1 expression in the penumbral cortex in the Sham, Control, YZR-0.2 g, YZR-0.4 g, and YZR-0.8 g groups (n = 5) at 1 day after reperfusion. Actin was used as an internal control in the Western blot analysis. The ratios of B p-ASK1/ASK1, C MyD88/actin, D TRAF6/actin, E T3JAM/actin, F TRAF3/actin, and G Iba1/actin were measured in the penumbral cortex among the experimental groups. cyto, cytosolic fraction. *P < 0.05 vs. the Sham group; #P < 0.05 vs. the Control group

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