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Fig. 8 | Chinese Medicine

Fig. 8

From: Potential mechanism of Ziyin Tongluo Formula in the treatment of postmenopausal osteoporosis: based on network pharmacology and ovariectomized rat model

Fig. 8

Effects of ZYTLF on expressions of key proteins. After treatment, the protein ERα (a), p38 MAPK (b), p-AKT (c), TGF-β1 (d), OPG (e), RANKL (f) expression of tibia in rats were measured by western blotting. The quantified amount of proteins was calibrated with the amount of GAPDH and then compared with the value of sham group. The statistics with Gaussian distribution were shown as the mean ± SD. Low: 1.34 g/kg; Middle: 2.68 g/kg; High: 4.02 g/kg; Western Medicine: alendronate 10.51 mg/kg per week and calcitriol 0.075 μg/kg per day. *p < 0.05, **p < 0.01 compared with OVX group

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