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Fig. 5 | Chinese Medicine

Fig. 5

From: A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model

Fig. 5

The results of network pharmacology prediction. A The herb-compound network. The ellipse nodes represent herbs, and the hexagon nodes are compounds. Among these compounds, yellow parts are the common components of Centella asiatica (L.) Urb. and Smilax glabra Roxb., and quercetin (red hexagon) is common compounds of 3 herbs. B The compound-target network. The V shape nodes represent 53 compounds, and the 765 yellow nodes are targets corresponding to the compounds. C The hypertension-target network. In this figure, the red node in the center is hypertension, and the green nodes represent gene targets. D The protein-protein interaction network within the common targets. It shows the relationship between 101 common targets. The size of nodes changes from big to small according to degree values, and the 12 yellow nodes are key targets after screening

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