Fig. 6

The OPLS-DA /permutation test/ S-plot/heatmaps indicating the intensities of effective biomarkers between CD and CD-NP Compounds 13, 15, 16, 37, 49, 63, 66, 72, 74, 75, and 85 are the differential components of CD, while compounds 10, 11, 32, 59, 60, 68, 70, 71, 80, 81, and 82 are the differential components of CD-NP.