Fig. 1
From: Advances in the study of emodin: an update on pharmacological properties and mechanistic basis
Networks of molecular signaling underlying anti-inflammatory and immunoregulative effects of emodin. Emodin limits immune and inflammation abnormality through inhibition of pro-inflammatory signaling pathways (such as TLR/NF-κB, PI3K/AKT, and JAK/STAT3) and NLRP3 inflammasome activation, induction of apoptosis, and regulation of microRNA expression as well as immune cells differentiation