Fig. 8From: Comparison of the chemical constituents and anti-Alzheimer’s disease effects of Uncaria rhynchophylla and Uncaria tomentosaThe schematic drawing summarizing the proposed mechanisms for the anti-neuroinflammatory and antioxidant effects of UTE and URE in the STZ-induced AD rat model. The mechanisms involve the inhibition of hyperphosphorylated tau protein, the promotion of antioxidant enzymes expression, the reduction of pro-inflammatory cytokines and the role of Akt (Ser473)/GSK3β (Ser9)-mediated Nrf2 activationBack to article page