Table 3 Table 3: The changed mRNAs are regulated by miRNAs in CUMS-induced rat depression model under LBRD standard decoction treatments
miRNAs | The predicted target mRNAs that match DEGs in transcriptomea |
|---|---|
rno-miR-879-5p ↓ | Calml4 ↑ Arc ↑ Gad1 ↑ |
rno-miR-7a-5p ↓ | Slc39a12 ↑ Ntrk2 ↑ GAT-3 ↑ |
rno-miR-499-5p ↓ | Calml4 ↑ |
rno-miR-495 ↓ | GAT-3 ↑ Calml4 ↑ Tnfaip6 ↑ Arc ↑ Gad1↑ Bdnf ↑ |
rno-miR-204-5p ↓ | Calml4 ↑ Ntrk2 ↑ VGAT ↑ |
rno-miR-199a-3p ↓ | Foxs1 ↑ Ntrk2 ↑ |
rno-miR-151-3p ↓ | Calml4 ↑ Ntrk2 ↑ |
rno-miR-144-3p ↓ | Calml4 ↑ Ntrk2 ↑ VGAT ↑ Gad1↑ |
rno-miR-24-3p ↓ | Nr1d1 ↑ |
rno-miR-25-3p ↓ | Btg2 ↑ GAT-3 ↑ VGAT ↑ |
rno-miR-21-5p ↓ | Btg2 ↑ Ntf3 ↑ |
rno-miR-494-3p ↑ | Acvr1c ↓ Syt6 ↓ |
rno-miR-380-5p ↑ | Acvr1c ↓ |
rno-miR-365-3p ↑ | Syt6 ↓ |
rno-miR-34c-5p ↑ | Flot2 ↓ Acvr1c ↓ Syt6 ↓ Il18bp ↓ |
rno-miR-346 ↑ | Dbp ↓ Acvr1c ↓ |
rno-miR-31a-5p ↑ | Flot2 ↓ Acvr1c ↓ Syt6 ↓ |
rno-miR-206-3p ↑ | Dbp ↓ Acvr1c ↓ |