Fig. 10
From: Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma
Aloin inhibited osteosarcoma growth in a xenograft model in BALB/c nude mice. A After 4 weeks of aloin treatment, the luciferase intensity of the tumors was measured at week 2 and week 4. B Gross observation showed significant differences among the control, aloin and cisplatin groups after 4 weeks. C IVIS intensity was measured by Living Image Software (v3.0.4). The cisplatin group was set for comparison, and the blank group was set as the sham-operated group. Error bar = mean ± SD of at least triplicate experiments. (* P < 0.005, **P < 0.01, ***P < 0.001, ****P < 0.0001)