Table 3 Aloin docking with key proteins
From: Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma
PDB ID | Score | Target gene | H bonds |
|---|---|---|---|
3CQW | −8.0 | AKT1 | ASP149(2.132 Å,2.223 Å), LEU152(1.875 Å), LYS36(1.965 Å) |
2ITX | −8.3 | EGFR | GLN791(2.079 Å,2.628 Å), MET793(2.264 Å, 2.353 Å,2.333 Å), ARG841(2.242 Å), THR790(2.216 Å) |
2H8H | −8.4 | SRC | ASN51(1.930 Å), LYS317(2.191 Å), GLU236(2.010 Å) |
3DEJ | −7.6 | CASP3 | ASP208(2.574 Å) |
1UKI | −8.0 | MAPK8 | ASP161(1.854,1.526 Å), CYS47(1.930 Å), GLN29 (2.226 Å) |
1W84 | −8.0 | MAPK14 | GLY107(2.274 Å,2.108 Å), ALA108(2.204 Å, 2.274 Å), ALA154(2.304 Å) |