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Table 1 The demographic and clinical biochemical indicators of participants

From: Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy

 

HC (n = 30)

CCQS (n = 44)

QSBS (n = 37)

p values

Basic information

 Age (year)

62.8 ± 9.4

67.2 ± 7.7

67.5 ± 7.8

0.048

 Female

17 (56.7)

25 (56.8)

21 (56.8)

1.000

 BMI (kg/m2)

24.7 ± 2.9

24.1 ± 3.9

25.2 ± 3.3

0.367

 Arrhythmia

6 (20)

6 (13.6)

6 (16.2)

0.768

 Diabetes mellitus

1 (3.3)

20 (45.5)

15 (40.5)

 < 0.001

 Hypertension

5 (16.7)

28 (63.6)

28 (75.7)

 < 0.001

 Hyperlipidemia

4 (13.3)

26 (59.1)

24 (64.9)

 < 0.001

 Cerebrovascular disease

2 (6.7)

4 (9.1)

15 (40.5)

 < 0.001

Laboratory data

 TC (mmol/L)

5.2 ± 1.0

4.4 ± 1

4.3 ± 0.9

0.001

 TG (mmol/L)

1.4 ± 0.9

1.5 ± 0.8

1.6 ± 0.7

0.704

 HDL (mmol/L)

1.5 ± 0.3

1.2 ± 0.2

1.3 ± 0.3

0.005

 LDL (mmol/L)

3.1 ± 0.8

2.6 ± 0.8

2.5 ± 0.7

0.002

 Albumin (g/L)

44.0 ± 2.1

44.1 ± 2.7

45 ± 5.9

0.532

 ALP (U/L)

89.9 ± 24.7

87.8 ± 20

86.4 ± 31.6

0.871

 ALT (U/L)

20.4 ± 10.9

22.2 ± 12

21.3 ± 10.5

0.800

 AST (U/L)

24.1 ± 5.1

24.5 ± 8.3

23.1 ± 6.1

0.665

 Creatinine (µmol/L)

61.8 ± 11.3

65 ± 16.8

63.6 ± 16.5

0.694

 GGT (U/L)

25.6 ± 16.9

29.5 ± 24.7

29.2 ± 17.4

0.717

 Glu (mmol/L)

5.8 ± 1.2

6.8 ± 1.9

6.6 ± 1.7

0.03

 HCY (µmol/L)

17.3 ± 13.5

14.9 ± 5.7

14.6 ± 5.3

0.377

 hs-CRP (mg/L)

1.9 ± 2.1

2 ± 2.2

1.6 ± 1.9

0.666

 Total protein (g/L)

74.4 ± 4.6

73.8 ± 4.7

73.4 ± 6.2

0.778

 Urea (mmol/L)

5.2 ± 1.0

5.5 ± 2

5.9 ± 1.9

0.315

 Uric acid (µmol/L)

305 ± 80.2

318.4 ± 79.9

344.3 ± 81

0.131

  1. Values were mean ± SD or %; p values determined by one-way ANOVA and χ2 test