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Fig. 3 | Chinese Medicine

Fig. 3

From: Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis

Fig. 3

Effects of SWT on intestinal barrier dysfunction and hepatic inflammation in mice with fibrotic liver injury. A Representative images of H&E staining of intestine tissues. Scale bar = 100 μm. B Relative mRNA levels of Il6, Ccl2 and Il1b in intestine tissues were determined by qPCR and normalized using Hprt1 as an internal control. C Relative mRNA levels of Ocln and Cdh1 in intestine tissues were determined by qPCR and normalized using Hprt1 as an internal control. D Representative images of ECAD staining of intestine tissues. Scale bar = 50 μm. E Relative mRNA levels of Il1b, Tnfa and Nos2 in liver tissues were determined by qPCR and normalized using Hprt1 as an internal control. Statistical significance: *P < 0.05, **P < 0.01, compared with control group; #P < 0.05, ##P < 0.01, ###P < 0.001, compared with CCl4 group. One-way ANOVA with Tukey’s post-hoc tests (n = 8)

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