Fig. 5
Effects of SWT on CCl4-mediated disturbance of gut microbiota and their associated biological functions. A The correlations between microbiota and samples were detected using Circos analysis. B Top 50 OTUs level classifiers for different groups were shown with phylogenetic tree. C Correlation network analysis of the 44 most abundant genera (P < 0.01). The lines between nodes indicated the Spearman correlation, and the color intensity indicated the correlation coefficient (red, positive; green, negative). Genera color were based on phylum affiliation, and sizes indicated mean relative abundance. D The relative abundance (%) of the top 10 bacteria (genus). E Relative abundance of pathogens, including Ruminococcaceae, Streptococcus, Alistipes and Rikenellaceae. F Relative abundance of probiotics, including Bacteroides, Lachnoclostridium, Lachnospiraceae and Prevotellaceae. G The analysis of COGs (left panel) and KEGG (right panel) pathways in Con, CCl4 and CCl4 + SWT groups. Statistical significance: *P < 0.05, **P < 0.01, ***P < 0.001, compared with control group; #P < 0.05, ##P < 0.01, ###P < 0.001, compared with CCl4 group. One-way ANOVA with Tukey’s post-hoc tests (n = 8)