Fig. 1

Curcumin decreased ROS in As³⁺ treated BEAS-2B cells, but increased ROS in As³⁺-induced transformed BEAS-2B cells. BEAS-2B cells were exposed to As³⁺ (10 μM) with or without curcumin (0, 3.125, 6.25, 12.5 μM) for 24 h and then were labeled with DCFDA (10 μM). A Images were taken with fluorescence microscopy and B fluorescent intensity determined by flow cytometry. C Cell viabilities were detected by staining with MTT assay. As³⁺-induced transformed BEAS-2B cells (AsT) were treated with curcumin (0, 3.125, 6.25, 12.5, 25 μM) for 24 h and then were labeled with DCFDA (10 μM). D Images were taken with fluorescence microscopy and E fluorescent intensity determined by flow cytometry. F Cell viabilities were detected by staining with MTT assay. The data are expressed as the mean ± SD of three independent experiments (n = 9). *p < 0.05, **p < 0.01 vs control. ^#p < 0.05, ^##p < 0.01 vs As³⁺ treatment only group