Fig. 6From: Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagySchematic of the role of HK in protecting hepatocytes against lipotoxicity. HK activates SIRT3, which in turn activates AMPK to enhance autophagy on LDs and deacetylates LCAD to increase fatty acid oxidation in mitochondria, resulting in attenuation of lipotoxicity in hepatocytesBack to article page