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Fig. 10 | Chinese Medicine

Fig. 10

From: Integrating network pharmacological and experimental models to investigate the therapeutic effects of baicalein in glaucoma

Fig. 10

a Representative TEM images showing ultrastructural changes in optic nerve tissue in different groups (bar = 2 μm; 1 μm). CON showed healthy optic nerve tissue. COH showed a small number of myelinated axons swollen (green arrow), thickness of myelin sheath increased, separation (red arrow) and vacuolation (*) of myelin sheath, mild swelling of mitochondria (black arrow). BAL showed partial myelinated axons diameter increasing, but tightly arranged. b Axon only (black, bar = 1 μm) and axon plus myelin (red, bar = 1 μm) diameter of each group were measured under high power (× 20,000). c Quantitative analysis of G-ratio among the three groups. n = 3. ****P < 0.0001

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