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Table 1 Origin, flavor, meridian tropism, and traditional uses of six TCMs used in THSWD

From: Traditional Chinese Medicine for adjuvant treatment of breast cancer: Taohong Siwu Decoction

TCM

REHMANNIAE RADIX (Dihuang, DH)

ANGELICAE SINENSIS RADIX (Danggui, DG)

PAEONIAE RADIX ALBA (Baishao, BS)

CHUANXIONG RHIZOMA (Chuanxiong, CX)

PERSICAE SEMEN

(Taoren, TR)

CARTHAMI FLOS (Honghua, HH)

Origin

Rehmannia glutinosa Libosch

Angelica sinensis(Oliv.)Diels

Paeonia lactiflora Pall

Ligusticum chuanxiong Hort

Prunus persica(L.)Batsch or Prunus davidiana(Carr.)Franch

Carthamus tinctorius L

Medicinal parts

Root tuber

Root

Root

Rhizome

Seed

Flower

Producing area

Henan, Liaoning, Hebei, Shandong Province

Gansu, Yunnan, Sichuan Province

Sichuan, Zhejiang, Anhui Province

Sichuan, Yunnan, Guizhou Province

Sichuan, Shaanxi, Shandong, Hebei Province

Sichuan, Henan, Hunan, Xinjiang Province

Preparation

Bake slowly until about 80% dry

firework slowly smokes dry

After boiled in boiling water, remove skin and dry

Sun-dried

Sun-dried

Shade or sun-dried

Dosage

10–15 g

6–12 g

6–15 g

3–10 g

5–10 g

3–10 g

Flavor and

meridian

tropism

Sweet, cold; heart, liver, and kidney

Sweet, pungent, and warm; liver, heart, and spleen

Sweet, pungent, warm; liver and spleen

pungent, and warm; liver, gallbladder

Bitter, sweet, calm; heart, liver, large intestine meridian

Sweet, pungent; heart, liver

Efficacy

To clear heat and cool blood, nourish yin and promote body fluid

To Replenish blood; promote blood circulation; regulate menstruation and relieve pain; moisturize dryness and smooth intestines

To expel wind and dampness, detoxify and antispasmodic

Invigorate qi to relieve depression, eliminate wind and dampness, promote blood circulation and relieve pain

To promote blood circulation and remove blood stasis, moisten the intestines and laxative, relieve cough and relieve asthma

To activate blood circulation, remove blood stasis and relieve pain

Traditional uses

Used for heat into the camp blood, warm toxins and spots, vomiting blood, blemishes, and heat injury to the yin

Various syndromes of blood deficiency; irregular menstruation; amenorrhea; dysmenorrhea

Blood deficiency, irregular menstruation, abdominal pain, limb contraction pain, headache and dizziness

Wind-cold headache, dizziness, hypochondriac pain, abdominal pain, cold arthralgia and tendons, amenorrhea

Amenorrhea, dysmenorrhea, lumps, pulmonary carbuncle, intestinal carbuncle, fall and flutter injury, dry intestines, constipation, cough and wheezing

Treatment of amenorrhea, dysmenorrhea, dystocia, stillbirth

Main chemical composition

Catalpol, Rehmannia Glucoside D

Ferulic acid, ligustilide

Paeoniflorin, albiflorin, total glucosides of paeony

Ferulic acid, ligustilide, ligustrazine

Amygdalin

Hydroxysafflor yellow A, kaempferol, quercetin

Pharmacological action

Blood system, cardiovascular system, orthopedics, central nervous system and immune system

Anti-tumor, anti-oxidation, inhibition of angiogenesis, anti-inflammatory and pain-relieving

Protecting cardiovascular, anti-inflammatory, and anti-oxidation

Anti-tumor, anti-inflammatory, anti-oxidation, and protection of the nervous system

Cardio-cerebral vascular protection, inhibits atherosclerosis, it can anticoagulant, inhibit platelet aggregation and improve blood rheology

Anti-myocardial ischemia, regulating hemodynamics, anti-inflammatory, analgesic, anti-oxidation, and regulating immunity