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Table 5 Correlation coefficients of the chemical composition variable groups and the pharmacological variable groups with VIP values of the compounds

From: Comparison of blood tonic efficacy and chemical constituents of Kadsura interior A.C. Smith and its closely related species

Compound

RBC#

HGB#

HCT

IL-3

GM-CSF#

M-CSF

BCA(r)

OPLSR (VIP)

BCA(r)

OPLSR (VIP)

BCA(r)

OPLSR (VIP)

BCA(r)

OPLSR (VIP)

BCA(r)

OPLSR (VIP)

BCA(r)

OPLSR (VIP)

Heteroclitin G

0.828

2.03

0.629

1.8594

0.252

2.0996

− 0.011

1.9421

0.7609

2.2051

0.6907

2.4739

Kadsutherin H

0.7842

0.1718

0.6386

0.1726

0.1364

0.1765

0.1298

0.165

0.6177

0.1765

0.6281

0.0188

Interiorin C

0.614

1.3025

0.858

1.4406

− 0.0287

1.2397

0.2238

1.3791

0.5701

1.3197

0.3061

0.7900

Kadsurin

0.4793

0.052

0.911

0.0578

− 0.1161

0.051

0.4774

0.0533

0.3995

0.0594

0.4301

0.0018

Heteroclitin D

0.6984

1.7646

0.82

1.834

0.0132

1.7267

0.1845

1.8059

0.5106

1.5206

0.4530

1.5014

Interiotherin C

0.6508

0.1504

0.6285

0.1502

0.2163

0.1507

0.0074

0.1497

0.5891

0.1489

0.5541

0.0129

Manwuwezic acid

0.1883

0.0903

0.6403

0.1319

− 0.0257

0.0784

0.1298

0.1051

0.2808

0.0995

0.0498

0.0063

Prinsepiol

0.4824

0.0685

− 0.0307

0.1698

− 0.0058

0.0966

− 0.1328

0.0313

0.2166

0.1232

0.6468

0.0313

Licarin A

0.633

0.0325

0.185

0.0408

0.365

0.0377

− 0.254

0.0265

0.7739

0.0448

0.6280

0.0018

  1. Compounds marked with bold text are with VIP value greater than 1 and Pearson correlation coefficients (r value) greater than 0.5, which could be considered as significant contribution to the classification to be used as an evaluation index for pharmacology. The OPLSR models built to represent these pharmacological indicators (#) are available