Fig. 6From: Perillaldehyde improves cognitive function in vivo and in vitro by inhibiting neuronal damage via blocking TRPM2/NMDAR pathwayPAE upregulated the protein expression of NR2B and downregulated the protein expression of TRPM2. A Fluo-3/AM was used to measure the cytosolic calcium concentration in hippocampal neurons (×800). B Immunofluorescence detection of NR2B and TRPM2 in hippocampal neurons (×200). C Quantitation of cytoplasmic Ca2+ fluorescence. D Quantitation of TRPM2 fluorescence expression intensity. E Quantitation of NR2B fluorescence expression intensity. All data is expressed as mean ± SEM. N is 6 in each group. *P < 0.05 vs. Model groupBack to article page