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Fig. 5 | Chinese Medicine

Fig. 5

From: Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression

Fig. 5

Western blot analysis of proteins associated with BDNF/TrkB signalling in dorsal hippocampal tissue from non-CRS + saline, CRS + saline, CRS + 10 mg/kg HE, and CRS + 25 mg/kg HE groups. Note, dividing lines represent cropped blots and white spaces represent cropped bands. Graphical representation of the effects of HE on the expression of neuroplasticity-related proteins (A) including TrkB (B), pTrkB (C), pro-BDNF (D), mature BDNF (E), CREB (F), and pCREB (G). The expression of target proteins was normalised to the expression of GAPDH. Note, there were significant increases in the expression of pTrkB, mBDNF, and pCREB proteins in the CRS + 25 mg/kg HE group compared with the CRS + saline group. *p ≤ 0.05. **p ≤ 0.01

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