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Fig. 10 | Chinese Medicine

Fig. 10

From: P2Y12 receptor as a new target for electroacupuncture relieving comorbidity of visceral pain and depression of inflammatory bowel disease

Fig. 10

P2Y12 receptor play an important role in IBD mice. a The expression of P2Y12 and IL-1β in mPFC of C57 mice. b Comorbidity of visceral pain and depression-like behaviors occurred in IBD mice and the expression of P2Y12 and IL-1β is increased in mPFC of IBD mice. c P2Y12 shRNA down-regulated the expression of P2Y12 and inhibited IL-1β expression in mPFC, thus relieving visceral pain and depression of IBD mice. d EA down-regulated the expression of P2Y12 and inhibited IL-1β expression in mPFC, thus relieving visceral pain and depression of IBD mice

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Chinese Medicine

ISSN: 1749-8546

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