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Fig. 4 | Chinese Medicine

Fig. 4

From: Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages

Fig. 4

Effects of LGZG on liver mitochondrial damage and oxidative stress in HFD-fed mice. a–c Representative Immunohistochemistry and Immunofluorescence images of liver sections from control and treated mice. For the staining of the expression of oxidative stress related markers, Livers sections were immune-stained with antibodies against 8-OHdG (a, DAPI staining), 4HNE (a, red fluorescent) and 3-NT (a, green fluorescent). b, c The relative expression of Nuclear-encoded Tert gene (b) and Cytosolic mtDNA content (c) in mice livers from control and treated mice. The relative expression of these genes were detected by qPCR and calculated with 2−△△CT. The data are expressed as mean ± SD (n = 9). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.001 vs. Mod group. The white scale bars represent 50 Î¼m

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