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Fig. 7 | Chinese Medicine

Fig. 7

From: Combination of pseudoephedrine and emodin ameliorates LPS-induced acute lung injury by regulating macrophage M1/M2 polarization through the VIP/cAMP/PKA pathway

Fig. 7

Pseudoephedrine + emodin Inhibited MAPK in LPS-induced acute lung injury in rats. A–D Western blot analysis was performed to detect p-P38, p-ERK1/2 and p-JNK1/2 protein expression. E–I TNF-α, IL-6, IL-1β, IL-10, Arg-1 mRNA expression was determined using Real-time PCR analysis. All data are expressed as mean ± S.D. (n = 3). ##p < 0.01, ###p < 0.001 vs. control group. *p < 0.05, **p < 0.01, ***p < 0.001 vs. LPS alone group. +p < 0.05, ++p < 0.01, +++p < 0.001 vs. Combined treatment group (5 + 20 mg/kg)

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