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Table 1 Applications of TCMPs in DDS

From: A review on the applications of Traditional Chinese medicine polysaccharides in drug delivery systems

Polysaccharide

DDS composition

Form

Function

Application

Ref.

BSP

DTX-SA-BSP

Copolymer micelle

Sustained release, pH sensitive, promoting absorption, enhancing stability

Anticancer

[31]

BSP

SM-hm-BSP

Copolymer micelle

Sustained release

Hepatic-targeted drug delivery

[32]

APS

APS-CMC-BSA

Hydrogel

Sustained release

–

[40]

BSP

PNS-BSP/alginate

Bioadhesive microsphere

Sustained release, synergistic effect

Gastric ulcers

[11, 17]

GLP

RCGDDH NPs

Conjugate

Redox and pH dual-responsive, synergistic effect

Anticancer

[16]

LBP

LBP-5ASA-Pt

Conjugate

Passive targeting (EPR)

Anti-lung cancer

[51]

BSP

Dox@FA-BSP-SA/TPGS

Copolymer micelle

FA-mediated active targeting, synergistic effect

Anticancer

[47]

BSP

DTX-BSP-ss-SA

Copolymer micelle

Redox and pH dual-responsive

Anticancer

[59]

ASP

DOX/ASP-DOCA

Copolymer micelle

pH sensitive, ASGPR-mediated active targeting

Hepatic-targeted drug delivery

[56]

ASP

Cur/ACNPs

Copolymer micelle

ASGPR-mediated active targeting

ALD

[45]

APS

quercetin-APS

Conjugate

Solubilization

–

[65]

VBCP

Baicalin/rhein-VBCP

Copolymer micelle

Solubilization

–

[63]

GPs

Ag-GPs

Nanoparticle

Enhancing stability

Antimicrobial biomaterials

[72]

ASP

AS-PBA/GA-CDB@Cur

Nanoparticle

Enhancing stability, pH sensitive

Antitumor

[83]

RP

CP3-DOX

Nanoparticle

Enhancing stability, promoting absorption, pH sensitive

Antitumor

[79]

BSP

LP-OBSP-CS

Hydrogel

Enhancing stability

Wound healing

[81]

OJP

THSG-OJP

Complexes

Enhancing solubility and stability

–

[64]

BSP

RB-BMNs

–

effective transdermal drug delivery

–

[94]

APS

Se-APS

Nanoparticle

Promoting absorption

Micro nutrient

[89]

LP

LP-Se

Nanoparticle

Promoting absorption

Anticancer

[90]