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Fig. 5 | Chinese Medicine

Fig. 5

From: Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice

Fig. 5

RYR reverses lipid synthesis via inhibiting mTORC1-SREBPs signaling in HFD-fed mice. A qPCR analysis of genes involved in lipogenesis-related genes in the liver, including SREBP-1, SREBP-2 and FASN. B Immunoblot analysis of mTOR, SREBP-1c, ACC and GPAT proteins related to lipogenesis in the liver (left) and their densitometric analysis (right, n = 3). C Hepatic expressions of proteins related to cholesterol metabolism, including SREBP-2, HMCGR, FDFT1, and LDLR (left) and their densitometric analysis results (right, n = 3). GAPDH was used as a control

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