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Fig. 6 | Chinese Medicine

Fig. 6

From: Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice

Fig. 6

RYR inhibits lipid accumulation and IL-1β secretion induced by LPS plus PA in HepG2 cells. A Cellular lipid droplets were measured by Oil Red O staining. B Cellular TG and TC levels (n = 4). C IL-1β in cell culture medium (n = 3). Data shown are individual values with means ± SEM. HepG2 cells were exposed to PBS plus 0.25 mM NaOH/1% BSA alone, LPS plus 0.25 mM PA/1% BSA, LPS plus 0.25 mM PA/1% BSA pretreated with 337 µg/mL, 674 µg/mL RYR, 50 µM lovastatin or 10 µM MCC950, respectively. **p<0.01, vs. control group. #p<0.05, ##p<0.01 vs. LPS plus PA group

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