Fig. 2

TFA ameliorated brain function and inhibited Aβ aggregated in type 2 diabetic mice. A H&E staining of mice hippocampus; B Brain volume ratio. C H&E staining of the brain (black arrow indicates the shrunken and hyperchromatic neurons; red arrow indicates the small empty bubble in the brain tissues; green arrow indicates the swollen, vacuolar neurons). D Immunohistochemistry and E ELISA detection of Aβ in the brain. *p < 0.05, **p < 0.01, vs. NC group; ^#p < 0.05, ^##p < 0.01, vs. T2DM group