Fig. 4
From: Revealing potential anti-fibrotic mechanism of Ganxianfang formula based on RNA sequence
RNA sequencing analysis. Liver tissues were from control rats(n = 8), model rats (CCl4-treated, n = 8) and GXF rats (CCl4 and 4.73 g/kg dose treated, n = 8). A Number of DEGs by RNA-seq of total liver mRNA. Genes upregulated or downregulated by more than twofold and p < 0.05 were shown in red and blue, respectively. B Significant KEGG pathways of compared groups as shown. C KEGG pathways of overlapped DEGs induced by GXF and CCl4, and important pathways were in red box. D Heatmap represented the gene expression of ECM-receptor interaction. Genes related were indicated. E Heatmap represented the gene expression of Chemokine signaling pathway. Genes related were indicated