Table 2 Comparison of treatment effect toward global assessment of improvement and other outcome measures
| Variable |
MZRW group (n = 27) |
Placebo group (n = 28) |
Between-Group Difference (95% CI) | P value |
|---|---|---|---|---|
| Primary Outcome | ||||
| Global assessment of improvementa, n (%) | 16 (59.26%) | 8 (28.57%) | NA | .022 |
| Secondary Outcomes (Changes from baseline) | ||||
| Stool frequency, mean (SD) | 2.46 (4.59) | 0.45 (1.71) | 2.02 (0.10 to 3.93) | .040 |
| Bristol stool type, mean (SD) | 0.89 (1.37) | 0.71 (1.61) | 0.17 (− 0.63 to 0.98) | .667 |
| Severity of constipation, mean (SD) | − 1.94 (2.22) | − 0.82 (1.67) | − 1.12 (− 2.19 to -0.05) | .040 |
| Sensation of straining, mean (SD) | − 1.09 (1.81) | − 0.02 (1.03) | − 1.07 (− 1.88 to -0.27) | .010 |
| Incomplete evacuation, mean (SD) | − 1.41 (2.28) | − 0.46 (2.04) | − 0.94 (− 2.11 to 0.23) | .112 |
| Bloating, mean (SD) | − 0.80 (1.97) | − 0.54 (1.91) | − 0.26 (− 1.31 to 0.79) | .621 |
| Abdominal pain/cramping, mean (SD) | − 0.26 (1.68) | 0.04 (1.43) | − 0.29 (− 1.14 to 0.55) | .485 |
| Nauseab, mean (SD) | − 0.15 (1.34) | 0.07 (1.76) | − 0.22 (− 1.07 to 0.63) | .606 |
| Passing of gas, mean (SD) | − 0.33 (1.83) | − 0.43 (1.70) | 0.10 (− 0.86 to 1.05) | .843 |