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Table 2 Corresponding relationships between bioactive ingredients and genes

From: Development of software enabling Chinese medicine-based precision treatment for osteoporosis at the gene and pathway levels

MolIdMolID

Bioactive ingredient in Drynariae Rhizoma

Bioactive ingredient-related gene

MOL000492

(+)-catechin

Beta-lactamase

MOL000492

(+)-catechin

Calmodulin

MOL000492

(+)-catechin

cAMP-dependent protein kinase catalytic subunit alpha

MOL000492

(+)-catechin

Estrogen receptor

MOL000492

(+)-catechin

Heat shock protein HSP 90-alpha

MOL000492

(+)-catechin

Hyaluronan synthase 2

MOL000492

(+)-catechin

Nuclear receptor coactivator 2

MOL000492

(+)-catechin

Prostaglandin G/H synthase 1

MOL000492

(+)-catechin

Prostaglandin G/H synthase 2

MOL000492

(+)-catechin

Retinoic acid receptor RXR-alpha

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Beta-lactamase

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

cAMP-dependent protein kinase catalytic subunit alpha

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Estrogen receptor

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Glucocorticoid receptor

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Heat shock protein HSP 90-alpha

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Mineralocorticoid receptor

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Progesterone receptor

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Prostaglandin G/H synthase 1

MOL001040

(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

Prostaglandin G/H synthase 2

MOL009061

22-Stigmasten-3-one

Progesterone receptor

MOL001978

Aureusidin

Androgen receptor

MOL001978

Aureusidin

cAMP-dependent protein kinase catalytic subunit alpha

MOL001978

Aureusidin

Carbonic anhydrase 2

MOL001978

Aureusidin

Cell division protein kinase 2

MOL001978

Aureusidin

Cyclin-A2

  1. MolID the ID number of the bioactive ingredients in Drynariae Rhizoma