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Table 2 Corresponding relationships between bioactive ingredients and genes

From: Development of software enabling Chinese medicine-based precision treatment for osteoporosis at the gene and pathway levels

MolIdMolID Bioactive ingredient in Drynariae Rhizoma Bioactive ingredient-related gene
MOL000492 (+)-catechin Beta-lactamase
MOL000492 (+)-catechin Calmodulin
MOL000492 (+)-catechin cAMP-dependent protein kinase catalytic subunit alpha
MOL000492 (+)-catechin Estrogen receptor
MOL000492 (+)-catechin Heat shock protein HSP 90-alpha
MOL000492 (+)-catechin Hyaluronan synthase 2
MOL000492 (+)-catechin Nuclear receptor coactivator 2
MOL000492 (+)-catechin Prostaglandin G/H synthase 1
MOL000492 (+)-catechin Prostaglandin G/H synthase 2
MOL000492 (+)-catechin Retinoic acid receptor RXR-alpha
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Beta-lactamase
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one cAMP-dependent protein kinase catalytic subunit alpha
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Estrogen receptor
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Glucocorticoid receptor
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Heat shock protein HSP 90-alpha
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Mineralocorticoid receptor
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Progesterone receptor
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Prostaglandin G/H synthase 1
MOL001040 (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Prostaglandin G/H synthase 2
MOL009061 22-Stigmasten-3-one Progesterone receptor
MOL001978 Aureusidin Androgen receptor
MOL001978 Aureusidin cAMP-dependent protein kinase catalytic subunit alpha
MOL001978 Aureusidin Carbonic anhydrase 2
MOL001978 Aureusidin Cell division protein kinase 2
MOL001978 Aureusidin Cyclin-A2
  1. MolID the ID number of the bioactive ingredients in Drynariae Rhizoma