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Table 3 Biochemical indexes for safety evaluation

From: Liushen Capsules, a promising clinical candidate for COVID-19, alleviates SARS-CoV-2-induced pulmonary in vivo and inhibits the proliferation of the variant virus strains in vitro

Biochemical indexes Patient A Patient B
Day1 Day7 Day1 Day7
ALT(IU/L) 13.3 15.8 14.1 6.7
AST(IU/L) 13.6 15.0 12.9 18.1
GGT(IU/L) 19.3 17.1 83.7 45.5
TBIL(μmol/L) 11.9 18.4 10.4 11.5
DBIL(μmol/L) 2.2 4.0 1.6 2.0
TP(g/L) 72.2 65.9 67.1 69.3
ALB(g/L) 45.1 42.0 41.0 42.6
TBA(μmol/L) 6.3 16.2 4.7 8.9
CCr(mL/min) 114 116.3 84.2 85.6
CREA(μmol/L) 63.7 62.4 94.10 96
UREA(μmol/L) 6.3 3.8 5.8 5.7
K(μmol/L) 3.84 3.77 4.29 3.99
Na(μmol/L) 138.8 140.2 141.9 142.3
Cl(μmol/L) 106.7 107.1 106.8 104.0
TCO2(μmol/L) 22.5 25.6 26.5 29.7
Ca(μmol/L) 2.28 2.40 2.30 2.33
GLU(μmol/L) 5.40 7.66 5.25 5.29
LDH(IU/L) 151.5 139 187.4 162.3
CK(IU/L) 60.8 61.4 31.3 40.1
CK-MB(IU/L) 12.0 12.0 5.0 3.0
HBDH(IU/L) 104.0 95.0 120.0 109.0
  1. ALT Alanine Aminotransferase, AST Aspartate Aminotransferase, GGT γ-glutamyl transpeptidase, TBIL Total Bilirubin, DBIL Direct Bilirubin, TP Total Protein, ALB albumin; TBA Total Bile Acids, CCr Creatinine Clearance, CREA creatinine, K Potassium ions, Na Sodium ion, Cl Chloride ion, TCO2 Total carbon dioxide, Ca Calcium ions, GLU Glucose; LDH Lactic Dehydrogenase, CK Creatine kinase, CK-MB creatine kinase-MB, HBDH hydroxybutyrate-dehydrogenase