Table 1 Demographic and baseline characteristics of patients between Ludangshen and placebo group
Characteristics | Ludangshen (n = 99) | Placebo (n = 98) | t/χ2/Z | P value |
|---|---|---|---|---|
Male (n, %) | 28 (28.3) | 33 (33.7) | 0.747 | 0.387 |
Age (n, %) | − 0.191 | 0.848 | ||
≤ 30 | 9 (9.1) | 5 (5.1) | ||
31–40 | 16 (16.2) | 23 (23.5) | ||
41–50 | 23 (23.2) | 21 (21.4) | ||
51–60 | 25 (25.3) | 18 (18.4) | ||
≥ 61 | 26 (26.3) | 31 (31.6) | ||
BMI (Mean ± SD) | 22.7 ± 2.86 | 23.7 ± 2.97 | − 2.236 | 0.021 |
Smoking (n, %) | 5 (5.0) | 9 (9.2) | 1.138 | 0.251 |
Drinking (n, %) | 4 (4.0) | 9 (9.2) | 2.168 | 0.141 |
Temperature (Median, IQR) | 36.5 (36.3–36.5) | 36.5 (36.3–36.5) | − 0.048 | 0.962 |
SBP (Mean ± SD) | 123.4 ± 11.2 | 124.2 ± 11.7 | − 0.512 | 0.609 |
DBP (Median, IQR) | 79 (73–81) | 76 (70–80.25) | − 0.799 | 0.424 |
Breathing (Median, IQR) | 18 (18–19) | 18 (18–19) | − 0.434 | 0.664 |
Resting heart rate (Median, IQR) | 80 (75–86) | 79.5 (75–86) | − 0.498 | 0.625 |
Clinical classification (n, %) | − 0.296 | 0.767 | ||
Mild cases | 10 (10.1) | 7 (7.1) | ||
Moderate cases | 77 (77.8) | 80 (81.6) | ||
Severe cases | 11 (11.1) | 11 (11.2) | ||
Critical cases | 1 (1.0) | 0 (0.0) | ||
CT imaging (n, %) | 0.359 | 0.549 | ||
Normal | 19 (19.2) | 22 (22.5) | ||
Abnormal | 80 (80.8) | 76 (77.6) | ||
Blood routine (n, %) | 1.221 | 0.269 | ||
Normal | 99 (100.0) | 94 (95.9) | ||
Abnormal | 0 (0.0) | 1 (1.0) | ||
Allergy history (n, %) | 16 (16.3) | 14 (14.3) | 0.133 | 0.737 |
Comorbidities (n, %) | 25 (25.3) | 27 (27.6) | 0.166 | 0.683 |
Initial symptoms (n, %) | ||||
Fatigue | 94 (94.9) | 90 (91.8) | – | – |
Anorexia | 68 (68.7) | 70 (71.4) | – | – |
Distention | 43 (43.4) | 34 (34.7) | – | – |
Loose stools | 48 (48.5) | 52 (53.1) | – | – |
Shortness of breath | 50 (50.5) | 50 (51.0) | – | – |
Concomitant medication (n, %) | 13 (13.1) | 15 (15.3) | 0.217 | 0.641 |
Hospitalization length (Median, IQR) | 19 (11–28) | 18 (10.75–26.5) | − 0.23 | 0.818 |
Discharge length (Median, IQR) | 71 (59–81) | 69.5 (50–80) | − 0.61 | 0.542 |