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Table 2 Comparison of symptom scores between Ludangshen and placebo group

From: Ludangshen oral liquid for treatment of convalescent COVID-19 patients: a randomized, double-blind, placebo-controlled multicenter trial

Variables FAS analysis PPS analysis
  Ludangshen Placebo P value Ludangshen Placebo P value
Fatigue (n) 94 90   92 92  
 Week 1 2.88 ± 1.44 3.64 ± 1.43  < 0.001 2.87 ± 1.45 3.51 ± 1.55  < 0.001
 Week 2 1.31 ± 1.42 3.21 ± 1.85  < 0.001 1.35 ± 1.46 3.11 ± 1.92  < 0.001
Anorexia (n) 68 70   67 68  
 Week 1 1.66 ± 1.17 2.61 ± 1. 53  < 0.001 1.66 ± 1.74 2.62 ± 1.55 0.535
 Week 2 0.78 ± 1.22 2.09 ± 1.74  < 0.001 0.78 ± 1.23 2.09 ± 1.76  < 0.001
Distention (n) 43 34   42 43  
 Week 1 2.02 ± 1.88 2.32 ± 2.10 0.024 2.00 ± 1. 90 2.27 ± 2.11 0.619
 Week 2 0.74 ± 1.62 1.53 ± 1.89 0.987 0.74 ± 1.64 1.58 ± 1.90 0.341
Loose stools (n) 48 52   48 50  
 Week 1 2.02 ± 1.77 2.65 ± 1.94 0.001 2.02 ± 1.77 2.70 ± 1.96 0.749
 Week 2 1.04 ± 1.91 2.12 ± 2.37 0.001 1.04 ± 1.91 2.20 ± 2.37 0.001
Shortness of breath (n) 50 50   49 49  
 Week 1 3.40 ± 1.36 4.02 ± 1.65 0.016 3.43 ± 1.35 4.02 ± 1.66 0.996
 Week 2 1.76 ± 1.38 3.26 ± 2.07 < 0.001 1.78 ± 1.396 3.27 ± 2.09  < 0.001
  1. FAS full analysis set, PPS per protocol set