Skip to main content

Table 2 Profiles of endocrine, metabolism, and liver function alterations in each group (n = 6)

From: Three-dimensional visualization of electroacupuncture-induced activation of brown adipose tissue via sympathetic innervation in PCOS rats

 

Control

Obesity

Obesity + EA

PCOS

PCOS + EA

Glucose metabolism

 Fasting insulin (uIU/ml)

15.38 ± 0.60

36.73 ± 1.75***

25.09 ± 1.33###

33.59 ± 2.06***

19.65 ± 1.68†††

 Fasting glucose (mmol/l)

5.03 ± 0.09

5.14 ± 0.17

4.91 ± 0.22

5.53 ± 0.09

4.76 ± 0.10††

OGTT

 Glucose 30 min (mmol/l)

8.35 ± 0.70

9.09 ± 0.40

8.01 ± 0.39

7.96 ± 0.31

7.23 ± 0.21

 Glucose 60 min (mmol/l)

7.78 ± 0.75

8.63 ± 0.51

8.30 ± 0.30

7.80 ± 0.22

7.65 ± 0.15

 Glucose 90 min (mmol/l)

6.43 ± 0.22

8.01 ± 0.45***

7.86 ± 0.20

6.56 ± 0.18

6.63 ± 0.13

 Glucose 120 min (mmol/l)

5.51 ± 0.70

7.16 ± 0.35***

7.13 ± 0.21

5.84 ± 0.15

5.49 ± 0.11

  Glucose AUC

13.10 ± 0.10

15.94 ± 0.69***

15.10 ± 0.19

14.00 ± 0.31**

13.31 ± 0.10††

  HOMA-IR

3.89 ± 0.20

9.17 ± 0.71***

5.89 ± 0.39##

7.89 ± 0.50***

4.69 ± 0.37††

Lipid profile

 TC (mmol/l)

1.90 ± 0.05

2.78 ± 0.06***

2.27 ± 0.08###

2.75 ± 0.07***

2.08 ± 0.08†††

 TG (mmol/l)

0.86 ± 0.04

1.44 ± 0.03***

1.10 ± 0.04##

1.35 ± 0.04***

1.01 ± 0.10††

 HDL-C (mmol/l)

0.99 ± 0.08

0.61 ± 0.05**

0.95 ± 0.08#

0.57 ± 0.08**

0.95 ± 0.11†

 LDL-C (mmol/l)

0.27 ± 0.01

0.36 ± 0.04*

0.29 ± 0.04

0.41 ± 0.05*

0.23 ± 0.04††

 Leptin (ng/ml)

1.41 ± 0.05

2.17 ± 0.12***

1.71 ± 0.12#

2.21 ± 0.22***

1.61 ± 0.09†

 ApoE (ng/ml)

72.10 ± 4.74

120.45 ± 7.71***

104.05 ± 4.12

138.20 ± 6.82***

87.09 ± 8.34†††

 FFA (nmol/ml)

300.26 ± 13.96

451.81 ± 28.97***

362.73 ± 8.62#

424.40 ± 30.81***

299.69 ± 20.85†

 Chemerin (ng/ml)

3.73 ± 0.20

6.13 ± 0.21***

4.93 ± 0.48#

5.90 ± 0.22***

5.01 ± 0.37

Liver function

 ALT (U/L)

20.69 ± 2.01

35.22 ± 1.92***

18.48 ± 1.84###

32.77 ± 3.66*

17.80 ± 3.11††

 AST (U/L)

20.04 ± 1.62

31.47 ± 1.30***

22.89 ± 1.93##

37.60 ± 3.06***

20.46 ± 2.16†††

 CRP (ug/ml)

3.212 ± 0.16

5.38 ± 0.38***

4.77 ± 0.23

5.73 ± 0.15***

4.14 ± 0.30†

 ALD (ng/L)

255.58 ± 16.30

508.22 ± 39.49***

343.88 ± 22.15##

475.56 ± 53.48**

297.08 ± 22.90†

  1. Results are presented as means ± SEM, and multiple comparisons between different groups were performed by one-way ANOVA. The bold showed the data with significant differences compared with either control or another two non-EA group. A p-value less than 0.05 was considered statistically significant
  2. TC total cholesterol, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, ApoE apolipoprotein E, FFA free fatty acid, OGTT oral glucose tolerance test, Glucose AUC area under curve = 0.5 × (BG0 + BG30)/2 + 0.5 × (BG30 + BG60)/2 + 0.5 × (BG60 + BG90)/2 + 0.5 × (BG90 + BG120)/2, HOMA-IR homeostatic model assessment for insulin resistance = fasting insulin (mU/l) × fasting glucose (mmol/l)/22.5, ALT alanine transaminase, AST aspartate transaminase, CRP C-reactive protein
  3. *p < 0.05, **p < 0.01, ***p < 0.001 vs. Control; #p < 0.05, # #p < 0.01, # ##p < 0.001 vs. Obesity; †p < 0.05, ††p < 0.01, †††p < 0.001 vs. PCOS
Back to article page

Chinese Medicine

ISSN: 1749-8546

Contact us