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Fig. 4 | Chinese Medicine

Fig. 4

From: Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice

Fig. 4

Effects of Persimmon leaf extract (PLE) on the synaptic plasticity in the cortex of mice subjected to chronic social defeat stress (CSDS). a Photomicrographs of Golgi-stained pyramidal neurons in the cortex of mice treated with PLE or fluoxetine for 10 days (scale bar: 50 μm). b Corresponding quantification data of the dendritic length in mice treated with PLE or fluoxetine for 10 days. c Total number of dendritic branching points in mice treated with PLE or fluoxetine for 10 days. d Photomicrographs of dendrite fragments with visible spines in the cortex of mice treated with PLE or fluoxetine for 10 days (scale bar: 10 μm). e Corresponding quantification data of dendritic spines. Data are presented as mean ± SD (n = 3 in each group). **P < 0.01 vs. Vehicle group; #P < 0.05, ##P < 0.01 vs. CSDS + Vehicle group

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