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Table 4 Pharmacologically active components found in SHL formula

From: Metabolomics analyses of traditional Chinese medicine formula Shuang Huang Lian by UHPLC-QTOF-MS/MS

No.

Name

PubChem CID

CAS

Reported pharmacological activity

1

Chlorogenic Acida

1794427

327-97-9

Antioxidant; antithrombotic; anti-influenza [37]; anti-bacterial [38]

2

Luteolin-7-O-glucosidea

5280637

5373-11-5

Antioxidant; anti-inflammatory [39]

3

Forsythoside Aa

5281773

79916-77-1

Anti-pyretic [40]

4

Baicalina

64982

21967-41-9

Anti-viral [41]

5

Forsythina

101712

487-41-2

Regulation of lipid [42]

6

Umbelliferone

5281426

93-35-6

Antioxidant; anti-cancer [43]

7

Piperonal

8438

120-57-0

Antiobesity [44]

8

Methyl caffeate

689075

3843-74-1

Antihyperglycemic and antidiabetic [45]

9

Danielone

146167

90426-22-5

Antifungal activity [46]

10

Geniposidic acid

443354

27741-01-1

Anti-tumor promoting activity [47]

11

Rutin

5280805

1340-08-5

Antimycobacterial [48]

12

Luteolin 3′-glucuronide

10253785

53527-42-7

Flavonoid, as a sedative and digestive [49]

13

Plumieride

72319

511-89-7

Immunostimulatory activity [50]

14

Brusatol

73432

14907-98-3

Anti-cancer (pancreatic cancer) [51]

15

Isovitexin

162350

29702-25-8

Anti-cancer [52]

16

Kaempferide

5281666

491-54-3

Protects against myocardial ischemia/reperfusion injury [53]

17

Baicalein

5281605

491-67-8

Anti-cancer (non-small cell lung cancer) [54]

18

Wogonin

5281703

632-85-9

Anti-cancer (lymphoma) [55]

19

Skullcapflavone II

124211

55084-08-7

Attenuates ovalbumin-induced allergic rhinitis [56]

20

Zwittermicin A

44474866

155547-95-8

Antibiotic, suppressing plant disease [57]

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