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Fig. 2 | Chinese Medicine

Fig. 2

From: Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury

Fig. 2

Geniposide alleviates cardiac damage caused by MI/R injury. A The protein expression of p-AMPK, AMPK, p-ACC, and ACC in mouse myocardium presented by representative western blot bands (n = 5). B The protein expression of p-AMPK and p-ACC in mice cardiac tissues of each group were shown by statistical histograms of representative western blots. C The representative DHE staining of the left ventricular of the mice, scale bar = 100 μm (n = 6). D Quantitative analyses of DHE staining level. E SOD2 activity of mouse heart samples were assayed using a commercial kit (n = 6). The data for each group were shown as the mean ± SD; #p < 0.05, ##p < 0.01 vs. Sham group; *p < 0.05, **p < 0.01 vs. I/R + Vehicle group

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