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Fig. 7 | Chinese Medicine

Fig. 7

From: Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress

Fig. 7

Treatment of CUMS-exposed rats with SSD results in elevated expression of PSD-95 and SYP in the hippocampal CA1 region. Images of IHC labeling at the original magnification (× 200 and × 400) and the respective IOD values of PSD-95 (A, B), and SYP (C, D) expression in the hippocampal tissue of CUMS-exposed rats. (E, F) show representative western blot images and the relative ratios of PSD-95 and SYP expression in the hippocampal CA1 regions of the different groups of CUMS-exposed rats. (G, H) show the PSD-95 and SYP mRNA levels in the hippocampal CA1 region of the rats in each group. All data are expressed as the mean ± SD. *P < 0.05 compared to the control group, #P < 0.05 compared to the CUMS group; n = 6

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