Table 1 The schedule of stressors used in CUMS paradigm

24-h water deprivation

1,15,27

overnight illumination

2,16,25,36

24-h food deprivation

3,19, 33,37

5-min heat exposure at 45 °C

10,20,31,

17-h white noise exposure

4,13,22, 26,41

17-h cage tilt at 45 degrees from the horizontal

5,21,29,34,40

24-h moist padding exposure

6,11,17,38

1-min tail pinch

8,12,18,23,30

3-h physical restraint

9,24,32,39

17-h strange object exposure

7,14,28,35,42