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Fig. 4 | Chinese Medicine

Fig. 4

From: Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling axis

Fig. 4

Network pharmacology analysis of SNKAF treating HCC. A The Venn analysis showed the crosstalk of DEGs in SNKAF and hepatocellular carcinoma; B PPI network of herb’s compound targets against HCC. The nodes with red borders represent the hub genes. C The GO enrichment analysis of potential targets by ClueGO, all data collected have a p-value ≤ 0.01. D The KEGG pathways enrichment analysis by ClueGO. All pathways have a p-value ≤ 0.01. E Gene target-pathway signal network, the green ellipse represents the different gene targets and the square colors represent the pathways

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