Table 3 Serum metabolites of RA EP patients
No. | Metabolite | m/z | RT (min) | Formula | VIP | Fold Change | Trend |
|---|---|---|---|---|---|---|---|
1 | Gamma-Aminobutyric acid | 104.11 | 8.16 | C4H9NO2 | 2.56 | -2.28 | ↓ |
2 | L-Homocysteic acid | 184.07 | 8.01 | C4H9NO5S | 4.74 | -2.72 | ↓ |
3 | S-Nitrosoglutathione | 337.06 | 0.62 | C10H16N4O7S | 10.03 | 2044.09 | ↑ |
4 | LysoPA(18:1(9Z)/0:0) | 459.25 | 8.01 | C21H41O7P | 1.01 | -2.12 | ↓ |
5 | LysoPE(P-16:0/0:0) | 438.30 | 8.35 | C21H44NO6P | 1.40 | -2.47 | ↓ |
6 | LysoPC(16:0/0:0) | 496.34 | 8.16 | C24H50NO7P | 38.02 | -2.29 | ↓ |
7 | LysoPC(P-18:0/0:0) | 508.38 | 8.55 | C26H54NO6P | 3.19 | -2.96 | ↓ |
8 | DG(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) | 685.44 | 11.50 | C43H66O5 | 1.24 | 3.42 | ↑ |
9 | Bisdiphosphoinositol tetrakisphosphate | 820.81 | 0.55 | C6H20O30P8 | 1.24 | 2.67 | ↑ |
10 | PE(22:0/24:0) | 888.80 | 0.55 | C51H102NO8P | 1.36 | 2.56 | ↑ |
11 | PC(24:0/24:1(15Z)) | 956.79 | 0.55 | C56H110NO8P | 1.29 | 2.36 | ↑ |
12 | Pyruvic acid | 174.96 | 0.49 | C3H4O3 | 4.84 | 15.21 | ↑ |
13 | D-Ribose | 130.97 | 0.49 | C5H10O5 | 2.13 | 9.07 | ↑ |
14 | L-Targinine | 187.07 | 0.60 | C7H16N4O2 | 1.68 | 53.79 | ↑ |
15 | N(omega)-Hydroxyarginine | 224.98 | 0.63 | C6H14N4O3 | 1.26 | -9.13 | ↓ |
16 | Citric acid | 191.02 | 0.64 | C6H8O7 | 2.66 | 6.12 | ↑ |
17 | Gamma-Glutamylserine | 269.08 | 0.60 | C8H14N2O6 | 4.21 | 52.50 | ↑ |
18 | 5-Thymidylic acid | 357.03 | 0.63 | C10H15N2O8P | 3.53 | 2.17 | ↑ |
19 | Inosinic acid | 329.04 | 0.59 | C10H13N4O8P | 5.62 | 124.17 | ↑ |
20 | SN38 glucuronide | 549.05 | 0.64 | C28H28N2O11 | 1.14 | 15.33 | ↑ |
21 | PC(O-22:1(13Z)/22:3(10Z,13Z,16Z)) | 878.77 | 0.48 | C52H98NO7P | 1.63 | 4.20 | ↑ |
22 | PE(22:0/24:1(15Z)) | 866.78 | 0.53 | C51H100NO8P | 1.91 | 3.57 | ↑ |
23 | Octanoyl-CoA | 874.24 | 0.48 | C29H50N7O17P3S | 1.21 | 3.57 | ↑ |
24 | PC(24:0/24:0) | 1002.76 | 0.53 | C56H112NO8P | 1.30 | 2.14 | ↑ |