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Fig. 5 | Chinese Medicine

Fig. 5

From: Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cells

Fig. 5

Salidroside inhibited ferroptosis by activating the Nrf2/HO1 pathway in Glu-injured HT22 cells. A-C The expression of Nrf2 and HO1 in the salidroside group were increased when compared with the Glu group. D, E Western blot showed that salidroside increased nuclear Nrf2 expression. F Immunofluorescence showed that salidroside increases the Nrf2 nuclear translocation in Glu-injured HT22 cells. G Nrf2 siRNA transfection efficiency on the HT22 cells. *P < 0.05, **P < 0.01, ***P < 0.001

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