Fig. 9From: Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cellsSalidroside regulated the expression of ferroptosis-related proteins in WT mice, but not in Nrf2−/−mice. Salidroside regulated the expression of GPX4, PTGS2, Nrf2 downstream antioxidant proteins NQO1, HO1 in hippocampus of WT mice, but it had no significant effects on Nrf2−/− mice. (n = 3 for each group), *P < 0.05, **P < 0.01, ***P < 0.001, “ns” means no significant difference (P > 0.05)Back to article page