Skip to main content
Fig. 4 | Chinese Medicine

Fig. 4

From: An anti-inflammatory and anti-fibrotic proprietary Chinese medicine nasal spray designated as Allergic Rhinitis Nose Drops (ARND) with potential to prevent SARS-CoV-2 coronavirus infection by targeting RBD (Delta)- angiotensin converting enzyme 2 (ACE2) binding

Fig. 4

ARND prevented SARS-CoV-2 pseudovirus infection of A549 lung cells. A A549 cells were pre-treated for 2 h with different concentrations of ARND followed by pseudovirus infection for 3 h (n = 4). Green fluorescent protein signal indicative of infection was examined and analyzed. ARND at all concentrations tested inhibited SARS-CoV-2 pseudovirus infection in A549 cells and (B) A549 cells were treated for 24 h with different concentrations of ARND (n = 4). The absorbance was measured with a microplate reader. ARND at all concentrations did not elicit > 50% reduction in viability of A549 cells. *p < 0.05, **p < 0.01 and ***p < 0.001 vs 0 µL/mL (0.5% DMSO)

Back to article page