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Fig. 5 | Chinese Medicine

Fig. 5

From: An anti-inflammatory and anti-fibrotic proprietary Chinese medicine nasal spray designated as Allergic Rhinitis Nose Drops (ARND) with potential to prevent SARS-CoV-2 coronavirus infection by targeting RBD (Delta)- angiotensin converting enzyme 2 (ACE2) binding

Fig. 5

ARND prevented SARS-CoV-2 pseudovirus infection of 293 T-ACE2 cells. (A) 293 T-ACE2 cells were first exposed for 2 h to ARND at different concentrations followed by pseudovirus infection for 3 h (n = 3). Green fluorescent protein signal indicative of infection was examined and analyzed. ARND at all concentrations tested inhibited SARS-CoV-2 pseudovirus infection of 293 T-ACE2 cells. (B) 293 T-ACE2 cells were treated for 24 h with different concentrations of ARND (n = 3). The absorbance was determined with a microplate reader. ARND at all concentrations did not elicit > 50% reduction in cell viability of 293 T-ACE2 cells. *p < 0.05, **p < 0.01 vs 0 µL/mL ARND (0.5% DMSO)

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Chinese Medicine

ISSN: 1749-8546

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